Glycerol-13C2

Modify Date: 2024-01-05 20:08:09

Glycerol-13C2 structure	Common Name	Glycerol-13C2
	CAS Number	102088-01-7	Molecular Weight	94.07910
	Density	1.288 g/mL at 25ºC	Boiling Point	182ºC(lit.)
	Molecular Formula	C₃H₈O₃	Melting Point	20ºC(lit.)
	MSDS	Chinese USA	Flash Point	320 °F(lit.)

Use of Glycerol-13C2

Glycerol-13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

Name	1,2,3-Propanetriol-1,3-13C2
Synonym	More Synonyms

Description	Glycerol-13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [3]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun18(3):213-9. [4]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20406(3):453-60.

Description

Glycerol-13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72.

[3]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun18(3):213-9.

[4]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20406(3):453-60.

Density	1.288 g/mL at 25ºC
Boiling Point	182ºC(lit.)
Melting Point	20ºC(lit.)
Molecular Formula	C₃H₈O₃
Molecular Weight	94.07910
Flash Point	320 °F(lit.)
Exact Mass	94.05410
PSA	60.69000
Index of Refraction	n20/D 1.474(lit.)

Glycerol-13C2 MSDS(Chinese)

Hazard Codes	Xi
Risk Phrases	R36/38
Safety Phrases	S26;S36
RIDADR	NONH for all modes of transport

Diethyl malonat...

CAS#:77386-82-4

Glycerol-13C2

CAS#:102088-01-7

Literature: Chen,T.S.; Chan,C.J.; Floss,H.G. Journal of the American Chemical Society, 1981 , vol. 103, p. 4565

Precursor 1
CAS#:77386-82-4 Diethyl malonat...
DownStream 3
CAS#:64-18-6 Formic Acid CAS#:1633-56-3 hydroxyformaldehyde CAS#:81277-97-6 2-13C-glycolic acid

MFCD00083974

Glycerin-1,3-13C2

GLYCEROL-1,3-13C2

GLYCEROL-1 3-13C2

[1,3-13C2]GLYCEROL

propane-1,2,3-triol

Glycerol-13C2

Use of Glycerol-13C2

Names

Glycerol-13C2 Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Synthetic Route

Precursor & DownStream

Synonyms