Tri(t-butoxycarbonylethoxymethyl) ethanol

Modify Date: 2024-01-21 07:43:52

Tri(t-butoxycarbonylethoxymethyl) ethanol Structure
Tri(t-butoxycarbonylethoxymethyl) ethanol structure
Common Name Tri(t-butoxycarbonylethoxymethyl) ethanol
CAS Number 1027581-61-8 Molecular Weight 520.65
Density N/A Boiling Point N/A
Molecular Formula C26H48O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tri(t-butoxycarbonylethoxymethyl) ethanol


Tri(t-butoxycarbonylethoxymethyl) ethanol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tri(t-butoxycarbonylethoxymethyl) ethanol

  Biological Activity

Description Tri(t-butoxycarbonylethoxymethyl) ethanol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C26H48O10
Molecular Weight 520.65
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