3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one

Modify Date: 2024-01-10 12:08:40

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure
3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one structure
Common Name 3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number 103343-47-1 Molecular Weight 251.283
Density 1.3±0.1 g/cm3 Boiling Point 456.7±45.0 °C at 760 mmHg
Molecular Formula C15H13N3O Melting Point N/A
MSDS N/A Flash Point 230.0±28.7 °C

 Names

Name 3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 456.7±45.0 °C at 760 mmHg
Molecular Formula C15H13N3O
Molecular Weight 251.283
Flash Point 230.0±28.7 °C
Exact Mass 251.105865
PSA 67.48000
LogP 1.45
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.684

 Safety Information

HS Code 2933990090

 Synthetic Route

~88%

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Sherrill; Sugg Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 730 - 734

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3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

~%

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

~%

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Bock, Mark G.; DiPardo, Robert M.; Evans, Ben E.; Rittle, Kenneth E.; Veber, Daniel F.; et al. Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3232 - 3239

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3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Glaxo Wellcome Inc. Patent: US5795887 A1, 1998 ; US 5795887 A

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3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

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3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

~%

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

~%

3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one Structure

3-amino-5-pheny...

CAS#:103343-47-1

Literature: Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-amino-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
3-(RS)-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
3-Amino-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine
3-amino-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
2H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-5-phenyl-
3-Amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
3-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
3-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
(3RS)-1,3-dihydro-3-amino-5-phenyl-2H-1,4-benzodiazepine-2-one
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