3-(2-hydroxyethyl)-2-methylquinazolin-4-one

Modify Date: 2024-01-19 16:51:18

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure
3-(2-hydroxyethyl)-2-methylquinazolin-4-one structure
Common Name 3-(2-hydroxyethyl)-2-methylquinazolin-4-one
CAS Number 10376-59-7 Molecular Weight 204.22500
Density 1.26g/cm3 Boiling Point 388.4ºC at 760mmHg
Molecular Formula C11H12N2O2 Melting Point N/A
MSDS N/A Flash Point 188.7ºC

 Names

Name 3-(2-hydroxyethyl)-2-methylquinazolin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.26g/cm3
Boiling Point 388.4ºC at 760mmHg
Molecular Formula C11H12N2O2
Molecular Weight 204.22500
Flash Point 188.7ºC
Exact Mass 204.09000
PSA 55.12000
LogP 0.69720
Vapour Pressure 9.98E-07mmHg at 25°C
Index of Refraction 1.617

 Synthetic Route

~97%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: DR.REDDY'S LABORATORIES LTD; DR.REDDY'S LABORATORIES LTD Patent: WO2006/29075 A2, 2006 ; Location in patent: Page/Page column 22 ; WO 2006/029075 A2

~%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: University of California; Yissum Research Development Company of the Hebrew University of Jerusalem; Biosignal LTD; Sugen, Inc.; Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V. Patent: US6331555 B1, 2001 ; US 6331555 B1

~85%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: Khan, Mahmud Tareq Hassan; Khan, Rasool; Wuxiuer, Yimingjiang; Arfan, Mohammad; Ahmed, Manzoor; Sylte, Ingebrigt Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4317 - 4327

~36%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: Dunn, A. D.; Kinnear, K. I.; Norrie, R.; Ringan, N.; Martin, D. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 175 - 180

~52%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: Jampilek, Josef; Musiol, Robert; Finster, Jacek; Pesko, Matus; Carroll, James; Kralova, Katarina; Vejsova, Marcela; O'Mahony, Jim; Coffey, Aidan; Dohnal, Jiri; Polanski, Jaroslaw Molecules, 2009 , vol. 14, # 10 p. 4246 - 4265

~%

3-(2-hydroxyethyl)-2-methylquinazolin-4-one Structure

3-(2-hydroxyeth...

CAS#:10376-59-7

Literature: Buzas; Hoffmann Bulletin de la Societe Chimique de France, 1959 , p. 1889

 Synonyms

2-methyl-3-hydroxyethyl quinazolin-4-one