Histatin-5 structure
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Common Name | Histatin-5 | ||
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CAS Number | 104339-66-4 | Molecular Weight | 3036.29000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C133H195N51O33 | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Name | histatin-5 |
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Synonym | More Synonyms |
Molecular Formula | C133H195N51O33 |
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Molecular Weight | 3036.29000 |
Exact Mass | 3034.51000 |
PSA | 1378.68000 |
LogP | 1.42620 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
Salivary histatin 5 induces non-lytic release of ATP from Candida albicans leading to cell death.
J. Biol. Chem. 274 , 18872, (1999) Salivary histatins are potent in vitro antifungal proteins and have promise as therapeutic agents against oral candidiasis. We performed pharmacological studies directed at understanding the biochemic... |
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Histatin 5 is a substrate and not an inhibitor of the Arg- and Lys-specific proteinases of Porphyromonas gingivalis.
Biochem. Biophys. Res. Commun. 250 , 474, (1998) The salivary peptide histatin 5 has been reported to be an inhibitor of the Arg- and Lys-specific proteinases of Porphyromonas gingivalis, an oral pathogen associated with periodontitis. In this study... |
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Salivary histatin as an inhibitor of a protease produced by the oral bacterium Bacteroides gingivalis.
Biochem. Biophys. Res. Commun. 174 , 625, (1991) We examined the effect of histatin 5 from human parotid saliva on various proteases. Histatin 5 strongly inhibited a trypsin-like protease produced by Bacteroides gingivalis with an IC50 value of 55 n... |
DSHAKRHHGYKRKFHEKHHSHRGY |
HISTATIN 5 (HUMAN) |
L-Asp-L-Ser-L-His-L-Ala-L-Lys-L-Arg-L-His-L-His-Gly-L-Tyr-L-Lys-L-Arg-L-Lys-L-Phe-L-His-L-Glu-L-Lys-L-His-L-His-L-Ser-L-His-L-Arg-Gly-L-Tyr-OH |
H-ASP-SER-HIS-ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR-OH |
ASP-SER-HIS-ALA-LYS-ARG-HIS-HIS-GLY-TYR-LYS-ARG-LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR |