Methylmalonyl coenzyme A tetralithium

Modify Date: 2024-01-06 12:36:48

Methylmalonyl coenzyme A tetralithium Structure
Methylmalonyl coenzyme A tetralithium structure
Common Name Methylmalonyl coenzyme A tetralithium
CAS Number 104809-02-1 Molecular Weight 891.34
Density 1.92g/cm3 Boiling Point N/A
Molecular Formula C25H36Li4N7O19P3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Methylmalonyl coenzyme A tetralithium


Methylmalonyl coenzyme A (Methylmalonyl-CoA) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1].

 Names

Name Methylmalonyl coenzyme A tetralithium salt hydrate
Synonym More Synonyms

 Methylmalonyl coenzyme A tetralithium Biological Activity

Description Methylmalonyl coenzyme A (Methylmalonyl-CoA) tetralithium is a catabolite of valine, isoleucine, methionine, threonine, odd-chain fatty acids, and cholesterol. Methylmalonyl coenzyme A is converted to succinyl-CoA by enzymatic reaction of methylmalonyl-CoA mutase (MCM) with coenzyme vitamin B12[1].
Related Catalog
References

[1]. Gotoh K, et al. Assay for methylmalonyl coenzyme A mutase activity based on determination of succinyl coenzyme A by ultrahigh-performance liquid chromatography tandem mass spectrometry. Anal Bioanal Chem. 2015 Jul;407(18):5281-6.  

 Chemical & Physical Properties

Density 1.92g/cm3
Molecular Formula C25H36Li4N7O19P3S
Molecular Weight 891.34
Exact Mass 867.13100
PSA 462.64000
LogP 0.64720
Index of Refraction 1.72
Storage condition 20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 22-26-36
RIDADR NONH for all modes of transport

 Articles4

More Articles
Adenosyltransferase tailors and delivers coenzyme B12.

Nat. Chem. Biol. 4 , 194-196, (2008)

The reactivity and relative rarity of most cofactors pose challenges for their delivery to target enzymes. Using kinetic analyses, we demonstrate that adenosyltransferase, which catalyzes the final st...

IcmF is a fusion between the radical B12 enzyme isobutyryl-CoA mutase and its G-protein chaperone.

J. Biol. Chem. 285 , 655-666, (2010)

Coenzyme B(12) is used by two highly similar radical enzymes, which catalyze carbon skeleton rearrangements, methylmalonyl-CoA mutase and isobutyryl-CoA mutase (ICM). ICM catalyzes the reversible inte...

CE assay of methylmalonyl-coenzyme-a mutase activity.

Electrophoresis 28 , 1921-1925, (2007)

Methylmalonyl-coenzyme A mutase (MCM) is a 5'-deoxyadenosylcobalamin-linked mitochondrial enzyme that catalyzes the isomerization of L-methylmalonyl-coenzyme A to succinyl-coenzyme A. We described a m...

 Synonyms

(2R)-3-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonatooxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-2-methyl-3-oxopropanoate