Cyclohexane-1,4-dimethanol

Modify Date: 2024-01-02 16:33:42

Cyclohexane-1,4-dimethanol Structure
Cyclohexane-1,4-dimethanol structure
Common Name Cyclohexane-1,4-dimethanol
CAS Number 105-08-8 Molecular Weight 144.211
Density 1.0±0.1 g/cm3 Boiling Point 286.2±8.0 °C at 760 mmHg
Molecular Formula C8H16O2 Melting Point 31.5 °C
MSDS Chinese USA Flash Point 161.1±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 1,4-Cyclohexanedimethanol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 286.2±8.0 °C at 760 mmHg
Melting Point 31.5 °C
Molecular Formula C8H16O2
Molecular Weight 144.211
Flash Point 161.1±0.0 °C
Exact Mass 144.115036
PSA 40.46000
LogP 0.36
Vapour density 5 (vs air)
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.471
Water Solubility MISCIBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU9800000
CHEMICAL NAME :
1,4-Cyclohexanedimethanol
CAS REGISTRY NUMBER :
105-08-8
LAST UPDATED :
199706
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H16-O2
MOLECULAR WEIGHT :
144.24
WISWESSER LINE NOTATION :
L6TJ A1Q D1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,194,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,194,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83552 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 1372 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83552 No. of Facilities: 37 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 1900 (estimated) No. of Female Employees: 63 (estimated)

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36
Safety Phrases S22-S24/25-S39-S26
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS GU9800000
HS Code 2906199090

 Synthetic Route

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Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: Angewandte Chemie - International Edition, , vol. 45, # 29 p. 4782 - 4785

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Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Detail
Literature: Angewandte Chemie - International Edition, , vol. 45, # 29 p. 4782 - 4785

~%

Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: WO2012/154204 A1, ; Page/Page column 83; 84 ;

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Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: Green Chemistry, , vol. 15, # 9 p. 2389 - 2393

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Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: WO2012/154204 A1, ;

~%

Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: WO2013/19441 A1, ;

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Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: WO2013/19441 A1, ;

~%

Cyclohexane-1,4-dimethanol Structure

Cyclohexane-1,4...

CAS#:105-08-8

Literature: WO2013/19441 A1, ; Paragraph 0110 ;

 Customs

HS Code 2906199090
Summary 2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles12

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A focused library of twenty-one cationic poly(amino ethers) was synthesized following ring-opening polymerization of two diglycidyl ethers by different oligoamines. The polymers were screened in paral...

A Processable Shape Memory Polymer System for Biomedical Applications.

Adv. Healthc. Mater. 4 , 1386-98, (2015)

Polyurethane shape memory polymers (SMPs) with tunable thermomechanical properties and advanced processing capabilities are synthesized, characterized, and implemented in the design of a microactuator...

Polyketal copolymers: a new acid-sensitive delivery vehicle for treating acute inflammatory diseases.

Bioconjug. Chem. 19(6) , 1164-9, (2008)

Acute inflammatory diseases are a major cause of death in the world, and effective treatments are greatly needed. Macrophages play a central role in causing acute inflammatory diseases, and there is c...

 Synonyms

EINECS 203-268-9
Cyclohexan-1,4-diyldimethanol
1,4-Chidm
Cyclohexane-1,4-dimethanol
α,α'-Dihydroxy-1,4-dimethylcyclohexane
1,4-Cyclohexanebismethanol
1,4-Cyclohexanedimet
1,4-Cyclohexanediyldimethanol
1,4-Bis(hydroxymethyl)cyclohexane
1,4-Cyclohexandimethanol
1,4-Cyclohexanedimethanol
CHDM
1,4-di(hydroxymethyl)cyclohexane
1,4-bis-hydroxymethylcyclohexane
[4-(hydroxymethyl)cyclohexyl]methan-1-ol
rikabinoldm
(4-Hydroxymethylcyclohexyl)methanol
MFCD00001512
Cyclohexane-1,4-diyldimethanol
1,4-DIMETHYLOLCYCLOHEXANE
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