N-acetyloxytocin

Modify Date: 2024-01-10 18:41:00

N-acetyloxytocin Structure
N-acetyloxytocin structure
Common Name N-acetyloxytocin
CAS Number 10551-48-1 Molecular Weight 1049.224
Density 1.4±0.1 g/cm3 Boiling Point 1593.2±65.0 °C at 760 mmHg
Molecular Formula C45H68N12O13S2 Melting Point N/A
MSDS N/A Flash Point 917.3±34.3 °C

 Use of N-acetyloxytocin


N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat[1].

 Names

Name 1-{[(4R,7S,10S,13S,16S,19R)-19-Acetamido-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-2-butanyl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide
Synonym More Synonyms

 N-acetyloxytocin Biological Activity

Description N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat[1].
Related Catalog
In Vitro Nα-acetylation is a post-translational modification of vasopressin (VP), and oxytocin (OT). The acetylated forms arc not restricted to the pineal gland, the tissue in which Nα-acetyl-OT is initially identified, but also occur in other systems producing OT and VP[1].
References

[1]. Liu B, et al. N-acetyl-vasopressin- and N-acetyl-oxytocin-like substances: isolation and characterization in the rat neurointermediate pituitary and presence in the brain. J Neuroendocrinol. 1989;1(1):47-52.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1593.2±65.0 °C at 760 mmHg
Molecular Formula C45H68N12O13S2
Molecular Weight 1049.224
Flash Point 917.3±34.3 °C
Exact Mass 1048.447021
LogP -3.89
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.628

 Synonyms

1-{[(4R,7S,10S,13S,16S,19R)-19-Acetamido-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-2-butanyl]-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-prolyl-L-leucylglycinamide
Glycinamide, 1-[[(4R,7S,10S,13S,16S,19R)-19-(acetylamino)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-leucyl-