(R)-(-)-O-Desmethyl Venlafaxine D6

Modify Date: 2024-01-04 19:59:01

(R)-(-)-O-Desmethyl Venlafaxine D6 structure	Common Name	(R)-(-)-O-Desmethyl Venlafaxine D6
	CAS Number	1062609-96-4	Molecular Weight	269.412
	Density	1.1±0.1 g/cm3	Boiling Point	403.8±25.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₉D₆NO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	193.2±21.8 °C

Use of (R)-(-)-O-Desmethyl Venlafaxine D6

(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

Name	4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol
Synonym	More Synonyms

Description	(R)-(-)-O-Desmethyl Venlafaxine D6 is the deuterium labeled (R)-(-)-O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine (HY-B0196) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

Description

Related Catalog

Research Areas >> Neurological Disease

References

[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28.

[2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.

Density	1.1±0.1 g/cm3
Boiling Point	403.8±25.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₉D₆NO₂
Molecular Weight	269.412
Flash Point	193.2±21.8 °C
Exact Mass	269.226196
LogP	2.26
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.573

4-[(1R)-2-{Bis[(2H3)methyl]amino}-1-(1-hydroxycyclohexyl)ethyl]phenol

Phenol, 4-[(1R)-2-(dimethyl-d3-amino)-1-(1-hydroxycyclohexyl)ethyl]-

(R)-(-)-O-Desmethyl Venlafaxine D6

Use of (R)-(-)-O-Desmethyl Venlafaxine D6

Names

(R)-(-)-O-Desmethyl Venlafaxine D6 Biological Activity

Chemical & Physical Properties

Synonyms