Sarcosine

Modify Date: 2024-01-02 16:44:15

Sarcosine Structure
Sarcosine structure
 Common Name Sarcosine
CAS Number 107-97-1 Molecular Weight 89.093
Density 1.1±0.1 g/cm3 Boiling Point 195.1±23.0 °C at 760 mmHg
Molecular Formula C3H7NO2 Melting Point 208-212 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 71.8±22.6 °C

 Use of Sarcosine


Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.

 Names

Name Sarcosine
Synonym More Synonyms

 Sarcosine Biological Activity

Description Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Zhang HX, et al. The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine. J Physiol. 2009 Jul 1;587(Pt 13):3207-20.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 195.1±23.0 °C at 760 mmHg
Melting Point 208-212 °C (dec.)(lit.)
Molecular Formula C3H7NO2
Molecular Weight 89.093
Flash Point 71.8±22.6 °C
Exact Mass 89.047676
PSA 49.33000
LogP -0.79
Vapour Pressure 0.2±0.8 mmHg at 25°C
Index of Refraction 1.431
Storage condition Store at RT.
Water Solubility 1480 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VQ2897000
CHEMICAL NAME :
Sarcosine
CAS REGISTRY NUMBER :
107-97-1
BEILSTEIN REFERENCE NO. :
1699442
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C3-H7-N-O2
MOLECULAR WEIGHT :
89.11

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS VQ2897000
HS Code 29224995

 Synthetic Route

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles87

More Articles
Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats.

Anesthesiology 121(1) , 160-9, (2014)

Dysfunction of spinal glycinergic neurotransmission is a major pathogenetic factor in neuropathic pain. The synaptic glycine concentration is controlled by the two glycine transporters (GlyT) 1 and 2....

Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods.

Anal. Sci. 31 , 805-14, (2015)

To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purit...

[Membrane-bound proteases of ompT+ and ompT- Vibrio cholerae strains].

Zh. Mikrobiol. Epidemiol. Immunobiol. (2) , 3-12, (2013)

Detection ofproteases in outer membranes (OM) of ompT+ and ompT- Vibrio cholerae strains of O1 and O139 serogroups.Specific sterile preparations of OM were obtained by lysis of live V. cholerae cells ...

 Synonyms

Acide (méthylamino)acétique
SAR
Glycine, N-methyl-
sarcosine zwitterion
MeNHCH2CO2H
MeHNCH2CO2H
EINECS 203-538-6
Methylaminoethanoic acid
N-methyl-Glycine
N-methylaminoacetic acid
Sarcosine
N-Methylglycocoll
N-Methylglycine
Methylaminoacetic Acid
MFCD00004279
(methylamino)-Acetic acid
H-Sar-OH
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Chemsrc provides Sarcosine(CAS#:107-97-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Sarcosine are included as well.>> amp version: Sarcosine

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