Lin28-IN-1632
Modify Date: 2024-02-05 10:36:44
Lin28-IN-1632 structure
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Common Name | Lin28-IN-1632 | ||
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| CAS Number | 108825-65-6 | Molecular Weight | 281.31300 | |
| Density | 1.28g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C15H15N5O | Melting Point | 200ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lin28-IN-1632Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells[1]. |
| Name | N-methyl-N-[3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide |
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| Synonym | More Synonyms |
| Description | Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits Lin28A binding to pre-let-7a-2, with an IC50 of 8 μM. Lin28-let-7 antagonist 1 inhibits proliferation in human cancer cells[1]. |
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| Related Catalog | |
| References |
[1]. Roos M, et al. A Small-Molecule Inhibitor of Lin28. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. |
| Density | 1.28g/cm3 |
|---|---|
| Melting Point | 200ºC |
| Molecular Formula | C15H15N5O |
| Molecular Weight | 281.31300 |
| Exact Mass | 281.12800 |
| PSA | 63.39000 |
| LogP | 2.08240 |
| Index of Refraction | 1.665 |
| Storage condition | -20°C |
| Hazard Codes | Xi: Irritant; |
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| Safety Phrases | S24/25 |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Acetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl] |
| N-Methyl-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide |