U0124

Modify Date: 2024-09-14 21:32:40

U0124 Structure
U0124 structure
Common Name U0124
CAS Number 108923-79-1 Molecular Weight 226.32200
Density 1.338g/cm3 Boiling Point 344.9ºC at 760mmHg
Molecular Formula C8H10N4S2 Melting Point N/A
MSDS N/A Flash Point 162.4ºC

 Use of U0124


U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM[1].

 Names

Name 2,3-bis[amino(methylsulfanyl)methylidene]butanedinitrile
Synonym More Synonyms

 U0124 Biological Activity

Description U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM[1].
Related Catalog
References

[1]. M F Favata, et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem. 1998 Jul 17;273(29):18623-32.

 Chemical & Physical Properties

Density 1.338g/cm3
Boiling Point 344.9ºC at 760mmHg
Molecular Formula C8H10N4S2
Molecular Weight 226.32200
Flash Point 162.4ºC
Exact Mass 226.03500
PSA 150.22000
LogP 2.50076
Vapour Pressure 6.37E-05mmHg at 25°C
Index of Refraction 1.647

 Synonyms

1,4-Diamino-1,4-bismethylthio-butadien-2,3-dicarbonitril
HMS3268M04