Ensituximab

Modify Date: 2024-02-03 17:37:04

Ensituximab Structure
Ensituximab structure
Common Name Ensituximab
CAS Number 1092658-06-4 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ensituximab


Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer[1][2].

 Names

Name Ensituximab

 Ensituximab Biological Activity

Description Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer[1][2].
Related Catalog
In Vitro Ensituximab (NPC-1C) 是一种嵌合 IgG1 单克隆抗体,在结合其靶标后促进抗体依赖性细胞的细胞毒性,MUC5AC 是一种肿瘤特异性变体,一种由结直肠癌 (CRC) 和胰腺癌特异性表达的抗原[1]。
References

[1]. Richard D Kim, et al. Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer. Clin Cancer Res. 2020 Jul 15;26(14):3557-3564.  

[2]. Julian A Marin-Acevedo, et al. Cancer immunotherapy beyond immune checkpoint inhibitors. J Hematol Oncol. 2018 Jan 12;11(1):8.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties