2-Ethoxyethyl ether

Modify Date: 2024-01-03 11:33:28

2-Ethoxyethyl ether Structure
2-Ethoxyethyl ether structure
Common Name 2-Ethoxyethyl ether
CAS Number 112-36-7 Molecular Weight 162.22700
Density 0.909 g/mL at 25 °C(lit.) Boiling Point 180-190 °C(lit.)
Molecular Formula C8H18O3 Melting Point -44.3 °C
MSDS Chinese USA Flash Point 160 °F
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1-ethoxy-2-(2-ethoxyethoxy)ethane
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.909 g/mL at 25 °C(lit.)
Boiling Point 180-190 °C(lit.)
Melting Point -44.3 °C
Molecular Formula C8H18O3
Molecular Weight 162.22700
Flash Point 160 °F
Exact Mass 162.12600
PSA 27.69000
LogP 1.07600
Vapour density 5.6 (vs air)
Vapour Pressure 0.758mmHg at 25°C
Index of Refraction n20/D 1.412(lit.)
Stability Stable. Combustible. Incompatible with strong oxidizing agents. May form peroxides on exposure to air - test for their presence before heating.
Water Solubility SOLUBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KN3160000
CHEMICAL NAME :
Ether, bis(2-ethoxyethyl)
CAS REGISTRY NUMBER :
112-36-7
BEILSTEIN REFERENCE NO. :
1699259
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C8-H18-O3
MOLECULAR WEIGHT :
162.26
WISWESSER LINE NOTATION :
2O2O2O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4970 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
6700 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1850 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
24 gm/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - stillbirth Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,141,1984
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3 gm/kg
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB88-168257 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84038 No. of Facilities: 1327 (estimated) No. of Industries: 7 No. of Occupations: 8 No. of Employees: 3060 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84038 No. of Facilities: 172 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 3489 (estimated) No. of Female Employees: 2128 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi: Irritant;
Risk Phrases R19
Safety Phrases S26-S36
WGK Germany 2
RTECS KN3160000
HS Code 29091900

 Synthetic Route

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2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Journal of the American Chemical Society, , vol. 47, p. 165

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Bulletin de la Societe Chimique de France, , p. 844,846 Journal de Chimie Physique et de Physico-Chimie Biologique, , vol. 54, p. 421,424

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Kaucuk Rez., , # 1 p. 51 Chem. Zentralbl., , vol. 108, # II p. 558 Canadian Journal of Research, , vol. 7, p. 465,466,470 Chem. Zentralbl., , vol. 104, # I p. 1759

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Barnakov, Ch. N.; Volgin, A. A. Russian Journal of Applied Chemistry, 1993 , vol. 66, # 1.2 p. 152 - 155 Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1993 , vol. 66, # 1 p. 182 - 185

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Journal of the American Chemical Society, , vol. 72, p. 405,407

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Chemische Berichte, , vol. 114, # 2 p. 477 - 487

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Canadian Journal of Research, , vol. 7, p. 465,466,470 Chem. Zentralbl., , vol. 104, # I p. 1759

~%

2-Ethoxyethyl ether Structure

2-Ethoxyethyl ether

CAS#:112-36-7

Literature: Kaucuk Rez., vol. 10, # 1 p. 51 Chem. Zentralbl., , vol. 108, # II p. 558 Canadian Journal of Research, , vol. 7, p. 465,466,470 Chem. Zentralbl., , vol. 104, # I p. 1759

 Customs

HS Code 2909199090
Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Articles3

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Results of testing fifteen glycol ethers in a short-term in vivo reproductive toxicity assay.

Environ. Health Perspect. 57 , 141-6, (1984)

Fifteen glycol ethers were investigated for their potential to cause adverse reproductive toxic effects using an in vivo mouse screening bioassay. Pregnant mice were orally dosed once per day on days ...

Density, viscosity, and surface tension at 293.15 K and liquid-liquid equilibria from 301.15 K to 363.15 K under atmospheric pressure for the binary mixture of diethylene glycol diethyl ether+ water. Li XX, et al.

J. Chem. Eng. Data 49(4) , 1043-1045, (2004)

Excess molar volumes and viscosities of binary mixtures of diethylene glycol diethyl ether with chloroalkanes at 298.15 K. Pal A and Bhardwaj RK.

J. Mol. Liq. 102(1) , 197-211, (2003)

 Synonyms

EINECS 203-963-7
Diethylene Glycol Diethyl Ether
Diethyldiglycol
Bis(2-ethoxyethyl) Ether
MFCD00009254
Diethyl Carbitol
2-Ethoxyethyl ether
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