tetraethylenepentamine

Modify Date: 2024-01-02 16:41:07

tetraethylenepentamine Structure
tetraethylenepentamine structure
Common Name tetraethylenepentamine
CAS Number 112-57-2 Molecular Weight 189.302
Density 1.0±0.1 g/cm3 Boiling Point 341.5±0.0 °C at 760 mmHg
Molecular Formula C8H23N5 Melting Point −40 °C(lit.)
MSDS Chinese USA Flash Point 185.0±0.0 °C
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

 Names

Name tetraethylenepentamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 341.5±0.0 °C at 760 mmHg
Melting Point −40 °C(lit.)
Molecular Formula C8H23N5
Molecular Weight 189.302
Flash Point 185.0±0.0 °C
Exact Mass 189.195343
PSA 88.13000
LogP -2.48
Vapour density 6.53 (vs air)
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.498
Stability Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, halogenated hydrocarbons, hydrogen peroxide.
Water Solubility SOLUBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH8585000
CHEMICAL NAME :
1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-((2-aminoethyl)amino)ethyl)-
CAS REGISTRY NUMBER :
112-57-2
BEILSTEIN REFERENCE NO. :
0506966
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C8-H23-N5
MOLECULAR WEIGHT :
189.36
WISWESSER LINE NOTATION :
Z2M2M2M2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3990 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
205 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
660 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
250 ug/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 320,31,1994 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84383 No. of Facilities: 798 (estimated) No. of Industries: 25 No. of Occupations: 25 No. of Employees: 17539 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84383 No. of Facilities: 1513 (estimated) No. of Industries: 45 No. of Occupations: 49 No. of Employees: 50358 (estimated) No. of Female Employees: 8280 (estimated)

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H302-H312-H314-H317-H411
Precautionary Statements P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;N:Dangerousfortheenvironment;
Risk Phrases R21/22;R34;R43;R51/53
Safety Phrases S26-S36/37/39-S45-S61
RIDADR UN 2320 8/PG 3
WGK Germany 2
RTECS KH8585000
Packaging Group III
Hazard Class 8
HS Code 29212900

 Synthetic Route

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Detail
Literature: WO2013/172675 A1, ; Page/Page column 16 ;

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Detail
Literature: WO2013/172675 A1, ; Page/Page column 10; 11; 13; 14 ;

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Literature: US2010/29976 A1, ; Page/Page column 8 ;

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CAS#:112-57-2

Literature: Inorganic Chemistry, , vol. 9, p. 2186 - 2188

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Detail
Literature: WO2010/42158 A1, ; Page/Page column 23-24 ;

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Literature: US2769841 , ;

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CAS#:112-57-2

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 9 p. 2098 - 2102,1868 - 1871

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CAS#:112-57-2

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 59, # 5.2 p. 1136 - 1140,1003 - 1007

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CAS#:112-57-2

Literature: Ullmann, 3 <1953> 132

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

1,2-Ethanediamine, N-(2-aminoethyl)-N-[2-[(2-aminoethyl)amino]ethyl]-
N-(2-Aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}-1,2-ethanediamine
TetraethylenepentaMine (so called)
N1-(2-Aminoethyl)-N2-(2-((2-aminoethyl)amino)ethyl)ethane-1,2-diamine
1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine
N-(2-Aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
tetraethylenepentamine
1,2-Ethanediamine, N- (2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
1,4,7,10,13-Pentaazatridecane
EINECS 203-986-2
MFCD00008168
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