Bromo-PEG1-C2-azide

Modify Date: 2024-01-16 17:05:13

Bromo-PEG1-C2-azide Structure
Bromo-PEG1-C2-azide structure
Common Name Bromo-PEG1-C2-azide
CAS Number 1144106-65-9 Molecular Weight 194.03
Density N/A Boiling Point N/A
Molecular Formula C4H8BrN3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG1-C2-azide


Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG1-C2-azide

 Bromo-PEG1-C2-azide Biological Activity

Description Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C4H8BrN3O
Molecular Weight 194.03