Bepafant

Modify Date: 2024-04-06 10:13:45

Bepafant Structure
Bepafant structure
Common Name Bepafant
CAS Number 114776-28-2 Molecular Weight 467.97100
Density 1.59g/cm3 Boiling Point 744.5ºC at 760mmHg
Molecular Formula C23H22ClN5O2S Melting Point N/A
MSDS N/A Flash Point 404.1ºC

 Use of Bepafant


Bepafant, also known as WEB-2170 and STY-2108, is a platelet activating factor (PAF) antagonist potentially for the treatment of asthma. Bepafant triggered apoptosis in NB4, KG1, and NB4-MR4 cells where PTEN was expressed, but not in THP1 and U937 cells where PTEN was absent. Bepafant may produce significant anti-inflammatory effects.

 Names

Name Bepafant
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.59g/cm3
Boiling Point 744.5ºC at 760mmHg
Molecular Formula C23H22ClN5O2S
Molecular Weight 467.97100
Flash Point 404.1ºC
Exact Mass 467.11800
PSA 100.85000
LogP 2.58870
Vapour Pressure 4.86E-22mmHg at 25°C
Index of Refraction 1.792

 Synonyms

6-(2-chlorophenyl)-8,9-dihydro-1-methyl-8-[(4-morpholinyl)carbonyl]-4H,7H-cyclopenta-[4,5]thieno-[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
Web 2170
4-((6-(o-chlorophenyl)-8,9-dihydro-1-methyl-4h,7h-cyclopenta[4,5]thieno[3,2-f]-s-triazolo[4,3-a][1,4]diazepin-8-yl)carbonyl)morpholine
Bepafanto [INN-Spanish]