CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UU7785800
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CHEMICAL NAME :
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4(1H)-Pyridinone, 1,2-diethyl-3-hydroxy-
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CAS REGISTRY NUMBER :
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115900-75-9
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LAST UPDATED :
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199709
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C9-H13-N-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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875 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 76,2389,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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52 gm/kg/52W-I
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TOXIC EFFECTS :
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Related to Chronic Data - death
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REFERENCE :
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MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 28(Suppl A),81,1992
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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42 gm/kg/15W-C
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TOXIC EFFECTS :
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Liver - other changes Biochemical - Metabolism (Intermediary) - porphyrin including bile pigments
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REFERENCE :
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BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 89,1045,1997
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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12 gm/kg/12W-I
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TOXIC EFFECTS :
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Liver - other changes Related to Chronic Data - death
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REFERENCE :
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BLOOAW Blood. (Grune & Stratton, Inc., 465 S. Lincoln Dr., Troy, MO 63379) V.1- 1946- Volume(issue)/page/year: 78,2727,1991
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