Tetrachlorophthalic anhydride

Modify Date: 2024-01-02 10:08:37

Tetrachlorophthalic anhydride structure	Common Name	Tetrachlorophthalic anhydride
	CAS Number	117-08-8	Molecular Weight	285.896
	Density	1.9±0.1 g/cm3	Boiling Point	371.0±0.0 °C at 760 mmHg
	Molecular Formula	C₈Cl₄O₃	Melting Point	253-257 °C(lit.)
	MSDS	Chinese USA	Flash Point	161.6±25.5 °C
	Symbol	GHS05, GHS08, GHS09	Signal Word	Danger

Name	tetrachlorophthalic anhydride
Synonym	More Synonyms

Density	1.9±0.1 g/cm3
Boiling Point	371.0±0.0 °C at 760 mmHg
Melting Point	253-257 °C(lit.)
Molecular Formula	C₈Cl₄O₃
Molecular Weight	285.896
Flash Point	161.6±25.5 °C
Exact Mass	283.860168
PSA	43.37000
LogP	3.56
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.656
Stability	Stable. Reacts with water. Combustible. Incompatible with strong oxidizing agents. Air and moisture sensitive.
Water Solubility	0.8 mg/L (21 ºC)

Tetrachlorophthalic anhydride MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI3450000

CHEMICAL NAME :: Phthalic anhydride, tetrachloro-

CAS REGISTRY NUMBER :: 117-08-8

BEILSTEIN REFERENCE NO. :: 0211560

LAST UPDATED :: 199712

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C8-Cl4-O3

MOLECULAR WEIGHT :: 285.88

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-93-3351 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-93-3351

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >3600 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-93-3351

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-93-3351 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 68250 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-93-3351

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 mg/m3/6H/13W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - changes in lung weight Endocrine - hyperglycemia Blood - changes in leukocyte (WBC) count

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538630 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3316 No. of Facilities: 55 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 142 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3316 No. of Facilities: 43 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 2067 (estimated) No. of Female Employees: 786 (estimated)

Symbol	GHS05, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H317-H318-H334-H350-H373-H410
Precautionary Statements	P201-P261-P273-P280-P305 + P351 + P338-P308 + P313
Hazard Codes	T:Toxic
Risk Phrases	R41;R42/43;R45;R50/53
Safety Phrases	S53-S22-S24-S26-S37/39-S45-S60-S61
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS	TI3450000
Packaging Group	III
Hazard Class	9
HS Code	2917399090

Precursor 8
CAS#:85-44-9 Phthalic anhydride CAS#:632-58-6 Tetrachlorophth... CAS#:84333-99-3 3,4,5,6-Tetrach... CAS#:91-20-3 Naphthalene
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DownStream 10
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HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Immunologic specificity of IgG against trimellityl-human serum albumin in serum samples of workers exposed to trimellitic anhydride.

J. Lab. Clin. Med. 121(6) , 792-6, (1993)

The specificity of immunoglobulin G (IgG) against trimellityl-human serum albumin (TM-HSA) in serum samples from 11 workers exposed to trimellitic anhydride (TMA) was characterized in this study. Leve...

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Tetrachlorophthalic anhydride

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MFCD00005920

EINECS 204-171-4