Brodalumab
Modify Date: 2024-04-08 20:04:56
Brodalumab structure
|
Common Name | Brodalumab | ||
|---|---|---|---|---|
| CAS Number | 1174395-19-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BrodalumabBrodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2]. |
| Name | Brodalumab |
|---|
| Description | Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IL-17R[1] |
| In Vitro | Brodalumab (AMG 827) 通过 IL-17RA/RC 复合物阻断 IL-17A、IL-17F 和 IL17-A/F 异源二聚体信号通路的生物活性，以及通过 IL-17RA/RB 复合物阻断 IL-25 (IL-17E) 信号通路的生物活性[2]。 Brodalumab 能够抑制银屑病的炎症过程[2]。 |
| References |
| Storage condition | 2-8°C |
|---|