LYG-202

Modify Date: 2024-01-11 18:09:58

LYG-202 Structure
LYG-202 structure
Common Name LYG-202
CAS Number 1175077-25-4 Molecular Weight 438.51600
Density N/A Boiling Point N/A
Molecular Formula C25H30N2O5 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

 Use of LYG-202


LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. LYG-202 inhibits VEGF-stimulated HUVEC migration and tube formation. LYG-202 induces cancer cell apoptosis[1][2].

 Names

Name 5-hydroxy-8-methoxy-7-(4-(4-methylpiperazin-1-yl)butoxy)-2-phenyl-4H-chromen-4-one
Synonym More Synonyms

 LYG-202 Biological Activity

Description LYG-202, a flavonoid, has potent anti-angiogenic and antitumor activity. LYG-202 inhibits VEGF-stimulated HUVEC migration and tube formation. LYG-202 induces cancer cell apoptosis[1][2].
Related Catalog
References

[1]. Chen Y, et al. LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo. J Pharmacol Sci. 2010;112(1):37-45.  

[2]. Zhao Y, et al. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells. Apoptosis. 2015 Sep;20(9):1253-69.  

 Chemical & Physical Properties

Molecular Formula C25H30N2O5
Molecular Weight 438.51600
Exact Mass 438.21500
PSA 75.38000
LogP 3.45640

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
RIDADR UN 2811 6.1 / PGIII

 Articles1

More Articles
Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis.

Cell Cycle 14 , 1704-15, (2015)

To maintain genome stability, the thousands of replication origins of mammalian genomes must only initiate replication once per cell cycle. This is achieved by a strict temporal separation of ongoing ...

 Synonyms

lyg-202
Top Suppliers:I want be here


Get all suppliers and price by the below link:

LYG-202 suppliers


Price: ¥1200/5 mg

Reference only. check more LYG-202 price