Pristanic acid

Modify Date: 2024-01-05 16:42:58

Pristanic acid Structure
Pristanic acid structure
Common Name Pristanic acid
CAS Number 1189-37-3 Molecular Weight 298.50400
Density 0.882g/cm3 Boiling Point 408ºC at 760 mmHg
Molecular Formula C19H38O2 Melting Point N/A
MSDS USA Flash Point 14ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of Pristanic acid


Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome[1][2][3].

 Names

Name pristanic acid
Synonym More Synonyms

 Pristanic acid Biological Activity

Description Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].
References

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. McLean BN, et al. A new defect of peroxisomal function involving pristanic acid: a case report. J Neurol Neurosurg Psychiatry. 2002 Mar;72(3):396-9.  

[3]. Baumgartner MR, et al. Clinical approach to inherited peroxisomal disorders: a series of 27 patients. Ann Neurol. 1998 Nov;44(5):720-30.  

 Chemical & Physical Properties

Density 0.882g/cm3
Boiling Point 408ºC at 760 mmHg
Molecular Formula C19H38O2
Molecular Weight 298.50400
Flash Point 14ºC
Exact Mass 298.28700
PSA 37.30000
LogP 6.14620
Appearance of Characters ethanol solution
Vapour Pressure 8.48E-08mmHg at 25°C
Index of Refraction 1.453
Storage condition −20°C

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H319
Precautionary Statements P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F: Flammable;
Risk Phrases R11
Safety Phrases S7
RIDADR UN 1170 3/PG 2
WGK Germany 1

 Synthetic Route

~%

Pristanic acid Structure

Pristanic acid

CAS#:1189-37-3

Literature: Smith; Boyack Journal of the American Chemical Society, 1948 , vol. 70, p. 2693

~%

Pristanic acid Structure

Pristanic acid

CAS#:1189-37-3

Literature: Eldjarn,L. et al. Acta Chemica Scandinavica (1947-1973), 1966 , vol. 20, p. 2313 - 2314

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles32

More Articles
New insights into the peroxisomal protein inventory: Acyl-CoA oxidases and -dehydrogenases are an ancient feature of peroxisomes.

Biochim. Biophys. Acta 1853(1) , 111-25, (2014)

Peroxisomes are ubiquitous organelles which participate in a variety of essential biochemical pathways. An intimate interrelationship between peroxisomes and mitochondria is emerging in mammals, where...

Peroxisomal bifunctional enzyme deficiency.

J. Clin. Invest. 83(3) , 771-7, (1989)

Peroxisomal function was evaluated in a male infant with clinical features of neonatal adrenoleukodystrophy. Very long chain fatty acid levels were elevated in both plasma and fibroblasts, and beta-ox...

Branched fatty acids in dairy and beef products markedly enhance alpha-methylacyl-CoA racemase expression in prostate cancer cells in vitro.

Cancer Epidemiol. Biomarkers Prev. 12(8) , 775-83, (2003)

An enzyme previously identified as alpha-methylacyl-CoA racemase (AMACR) is overexpressed in high-grade prostatic intraepithelial neoplasia and in a majority (60-100%) of prostate cancers (CaPs) as co...

 Synonyms

(2S,6R,10R)-2,6,10,14-tetramethylpentadecanoic acid
Pristaninsaeure
acide pristanique
Pristanic acid solution
2,6,10,14-Tetramethyl-pentadecansaeure
2,6,10,14-tetramethylpentadecanoic
acido pristanico
2,6,10,14-Tetramethylpentadecanoic acid
2,6,10,14-tetramethyl-pentadecanoic acid
MFCD05664739
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