Trt-PEG4-C2-acid hydrate

Modify Date: 2024-01-04 08:42:19

Trt-PEG4-C2-acid hydrate Structure
Trt-PEG4-C2-acid hydrate structure
Common Name Trt-PEG4-C2-acid hydrate
CAS Number 1189873-11-7 Molecular Weight 542.68
Density N/A Boiling Point N/A
Molecular Formula C30H38O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Trt-PEG4-C2-acid hydrate


Trt-PEG4-C2-acid (hydrate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Trt-PEG4-C2-acid hydrate

 Trt-PEG4-C2-acid hydrate Biological Activity

Description Trt-PEG4-C2-acid (hydrate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C30H38O7S
Molecular Weight 542.68