5-O-Desmethyl donepezil-d5

Modify Date: 2024-01-22 11:00:36

5-O-Desmethyl donepezil-d5 Structure
5-O-Desmethyl donepezil-d5 structure
Common Name 5-O-Desmethyl donepezil-d5
CAS Number 1189929-21-2 Molecular Weight 370.50
Density N/A Boiling Point N/A
Molecular Formula C23H22D5NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-O-Desmethyl donepezil-d5


5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.

 Names

Name 5-hydroxy-6-methoxy-2-[[1-[(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-4-yl]methyl]-2,3-dihydroinden-1-one
Synonym More Synonyms

 5-O-Desmethyl donepezil-d5 Biological Activity

Description 5-O-Desmethyl donepezil-d5 is deuterium labeled 5-O-Desmethyl donepezil.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C23H22D5NO3
Molecular Weight 370.50
Exact Mass 370.23000
PSA 49.77000
LogP 3.99600

 Synonyms

5-O-Desmethyl Donepezil-d5