N-((2S)-4-(3-(2-aminocyclopropyl)phenoxy)-1-(benzylamino)-1-oxobutan-2-yl)benzamidehydrochloride

N-[(1S)-3-[3-(2-aminocyclopropyl)phenoxy]-1-
[[(phenylmethyl)amino]carbonyl]propyl]-, hydrochloride
(1:1) (CA INDEX NAME)
Chemical FormulaC27H29N3O3·HCl
1196052-98-8
CAS Number

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Section II.Composition and Information on Ingredients
Chemical NameCAS Number Percent (%)TLV/PELToxicology Data
N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy]1196052-98-8Min. 97.0 Not available.Not available.
-1-(benzylcarbamoyl)propyl]benzamide Hydrochloride(HPLC)

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Section III. Hazards Identification
No specific information is available in our data base regarding the toxic effects of this material for humans. However,
Acute Health Effects
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.

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Section IV.First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
Eye Contact
minutes. Get medical attention.
Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing
before reuse. Thoroughly clean shoes before reuse. Get medical attention.
InhalationIf the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
improve.
IngestionINDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic
material was ingested; the absence of such signs, however, is not conclusive.

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Section V.Fire and Explosion Data
Not available.
Auto-Ignition
FlammabilityMay be combustible at high temperature.
Flammable LimitsNot available.
Flash PointsNot available.
Combustion ProductsThese products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), halogenated compounds.
WARNING: Highly toxic HCl gas is produced during combustion.
Fire HazardsNot available.
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards
Risks of explosion of the product in presence of static discharge: Not available.
Continued on Next Page
N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy]
-1-(benzylcarbamoyl)propyl]benzamide Hydrochloride
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
and Instructions
Consult with local fire authorities before attempting large scale fire-fighting operations.

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Section VI.Accidental Release Measures
Spill CleanupHygroscopic material. Heat sensitive material.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
Instructions
contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
disposal.

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Section VII. Handling and Storage
Handling and StorageHYGROSCOPIC. HEAT SENSITIVE. STORE UNDER ARGON. REFRIGERATE. Keep away from heat. Mechanical
exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light.
Information
Do not breathe dust.
Always store away from incompatible compounds such as oxidizing agents, moisture.

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Section VIII. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Personal ProtectionSplash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Exposure LimitsNot available.

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Section IX. Physical and Chemical Properties
Solid. (Crystal, powder. White, yellowishSolubility
Physical state @ 20°CNot available.
grey.)
Not available.
Specific Gravity
Molecular Weight480.00Partition Coefficient
Not available.
Boiling PointNot available.Vapor PressureNot applicable.
139°C (282.2°F)Not available.
Melting PointVapor Density
Refractive IndexNot available.VolatilityNot available.
Not available.Not available.
Critical TemperatureOdor
ViscosityNot available.TasteNot available.

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Section X.Stability and Reactivity Data

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This material is stable if stored under proper conditions. (See Section VII for instructions)
Stability
Conditions of InstabilityAvoid excessive heat and light. Hygroscopic; keep container tightly closed.
Incompatibilities
Reactive with oxidizing agents, moisture.

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Section XI. Toxicological Information
Not available.
RTECS Number
Eye Contact. Ingestion. Inhalation.
Routes of Exposure
Not available.
Toxicity Data
Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
Acute Toxic EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However,
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this
compound.
Continued on Next Page
N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy]
-1-(benzylcarbamoyl)propyl]benzamide Hydrochloride

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Section XII.Ecological Information
Not available.
Ecotoxicity
Environmental FateNot available.

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Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a
Waste Disposal
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state and local regulations when disposing of the substance.

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Section XIV. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
PIN NumberNot applicable.
Proper Shipping NameNot applicable.
Packing Group (PG)Not applicable.
DOT Pictograms

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Section XV. Other Regulatory Information and Pictograms
TSCA Chemical InventoryThis product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS ClassificationNot controlled under WHMIS (Canada).
(Canada)
EINECS Number (EEC)Not available.
EEC Risk Statements
Not available.

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SECTION 16 - ADDITIONAL INFORMATION
N/A