(4-Aminophenyl)acetic acid

Modify Date: 2024-01-02 11:55:30

(4-Aminophenyl)acetic acid Structure
(4-Aminophenyl)acetic acid structure
Common Name (4-Aminophenyl)acetic acid
CAS Number 1197-55-3 Molecular Weight 151.163
Density 1.3±0.1 g/cm3 Boiling Point 344.0±17.0 °C at 760 mmHg
Molecular Formula C8H9NO2 Melting Point 201 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 161.9±20.9 °C

 Names

Name 4-Aminophenylacetic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 344.0±17.0 °C at 760 mmHg
Melting Point 201 °C (dec.)(lit.)
Molecular Formula C8H9NO2
Molecular Weight 151.163
Flash Point 161.9±20.9 °C
Exact Mass 151.063324
PSA 63.32000
LogP 0.22
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.615

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AF3550000
CHEMICAL NAME :
Acetic acid, (p-aminophenyl)-
CAS REGISTRY NUMBER :
1197-55-3
BEILSTEIN REFERENCE NO. :
2208094
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H9-N-O2
MOLECULAR WEIGHT :
151.18
WISWESSER LINE NOTATION :
ZR D1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
2500 ug/plate
REFERENCE :
DEMAEP Dental Materials. (Munksgaard International Pub., POB 2148, DK-1016 Copenhagen K, Denmark) V.1- 1985- Volume(issue)/page/year: 2,163,1986

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AF3550000
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2922499990
Summary HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

 Articles5

More Articles
4-aminomethylbenzoic acid is a non-translocated competitive inhibitor of the epithelial peptide transporter PepT1.

J. Physiol. 512 ( Pt 3) , 629-34, (1998)

1. 4-Aminomethylbenzoic acid, a molecule which mimics the special configuration of a dipeptide, competitively inhibits peptide influx in both Xenopus Laevis oocytes expressing rabbit PepT1 and through...

Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity.

Acta. Pharm. 56(3) , 273-84, (2006)

Condensation of 4-aminophenylacetic acid with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid (1), which was employed as the key intermediate in the synthesis of title compounds 2-8. T...

Peptide mimics as substrates for the intestinal peptide transporter.

J. Biol. Chem. 273(1) , 20-2, (1998)

4-Aminophenylacetic acid (4-APAA), a peptide mimic lacking a peptide bond, has been shown to interact with a proton-coupled oligopeptide transporter using a number of different experimental approaches...

 Synonyms

UNII:1IED47A544
(4-AMINO-PHENYL)-ACETIC ACID
4-aminophenyl-acetic acid
4-Aminobenzeneacetic acid
p-Aminophenylacetic Acid
4-(AMINOPHENYL)ACETIC ACID
2-(4-aminophenyl)acetic acid
(4-AMINOPHENYL)ACETICACID
Phenylglycine base
MFCD00007916
4-AMINOPHENYLACETIC ACID FOR SYNTHESIS
(4-AMINOPHENYL)ACETIC ACID
EINECS 214-828-7
4-Aminophenylacetic acid
H-4-APH-OH
4-Carboxymethylaniline
RARECHEM AL BO 0220
Benzeneacetic acid, 4-amino-
BENZENEACETICACID, 4-AMINO-
4-Aminophenylacetic
DL-Phenylglycine
(para-Aminophenyl)acetic acid
Desacetyl Actarit
4-AMino acid
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