clerodendrin

Modify Date: 2024-02-01 13:39:37

clerodendrin Structure
clerodendrin structure
Common Name clerodendrin
CAS Number 119738-57-7 Molecular Weight 622.48500
Density 1.88g/cm3 Boiling Point 1057.6ºC at 760mmHg
Molecular Formula C27H26O17 Melting Point N/A
MSDS N/A Flash Point 349.9ºC

 Use of clerodendrin


Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].

 Names

Name (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-6-carboxy-4,5-dihydroxy-2-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonym More Synonyms

 clerodendrin Biological Activity

Description Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].
Related Catalog
In Vitro Clerodendrin (10 μM; 1 and 3 h) inhibits IL-4 mRNA expression and the release of β-hexosaminidase in Propidium Iodide (HY-D0815)-induced RBL-2H3 cells[1].
References

[1]. Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27(4):251-6.

 Chemical & Physical Properties

Density 1.88g/cm3
Boiling Point 1057.6ºC at 760mmHg
Molecular Formula C27H26O17
Molecular Weight 622.48500
Flash Point 349.9ºC
Exact Mass 622.11700
PSA 283.34000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.766
Storage condition 2-8°C

 Synonyms

Clerodendrin