4-METHYLCATECHOL-D8

Modify Date: 2024-01-02 09:12:24

4-METHYLCATECHOL-D8 structure	Common Name	4-METHYLCATECHOL-D8
	CAS Number	1219803-18-5	Molecular Weight	132.186514224
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇D₈O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 4-METHYLCATECHOL-D8

4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].

Name	4-METHYLCATECHOL-D8

Description	4-Methylcatechol-d8 is the deuterium labeled 4-Methylcatechol[1]. 4-Methylcatechol, a metabolite of p-toluate, is a substrate as well as a suicide inhibitor of Catechol 2,3-Dioxygenase[2].
Related Catalog	Research Areas >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Okuta A, et al. Construction of chimeric catechol 2,3-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.

Molecular Formula	C₇D₈O₂
Molecular Weight	132.186514224