4-Nitrobenzoyl chloride

Modify Date: 2024-01-02 22:58:41

4-Nitrobenzoyl chloride Structure
4-Nitrobenzoyl chloride structure
Common Name 4-Nitrobenzoyl chloride
CAS Number 122-04-3 Molecular Weight 185.565
Density 1.5±0.1 g/cm3 Boiling Point 277.8±13.0 °C at 760 mmHg
Molecular Formula C7H4ClNO3 Melting Point 71-74 °C(lit.)
MSDS Chinese USA Flash Point 121.8±19.8 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 4-Nitrobenzoyl chloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 277.8±13.0 °C at 760 mmHg
Melting Point 71-74 °C(lit.)
Molecular Formula C7H4ClNO3
Molecular Weight 185.565
Flash Point 121.8±19.8 °C
Exact Mass 184.987976
PSA 62.89000
LogP 2.17
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.589
Stability Stability Stable, but moisture sensitive. Combustible. Incompatible with water, alcohols, strong oxidizing agents, strong bases.
Water Solubility Decomposes

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM6651000
CHEMICAL NAME :
Benzoyl chloride, p-nitro-
CAS REGISTRY NUMBER :
122-04-3
BEILSTEIN REFERENCE NO. :
0473192
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C7-H4-Cl-N-O3
MOLECULAR WEIGHT :
185.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5600 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Behavioral - muscle contraction or spasticity
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3440 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Behavioral - muscle contraction or spasticity
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
4750 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Behavioral - ataxia Behavioral - muscle contraction or spasticity
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16800 mg/kg/30D-I
TOXIC EFFECTS :
Blood - other changes
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
11830 ug/m3/4H/17W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Blood - pigmented or nucleated red blood cells Blood - changes in spleen
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
11830 ug/m3/4H
SEX/DURATION :
male 16 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
3 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3261 8/PG 2
WGK Germany 2
RTECS DM6651000
Packaging Group II
Hazard Class 8
HS Code 2916399090

 Synthetic Route

 Customs

HS Code 2916399090
Summary 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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 Synonyms

4-Nitrobenzoyl chloride
p-NO2-PhCO3tBu
para-nitrobenzoyl chloride
4 NITRO BENZOYL CHLORIDE
P-NITRO BENZOYL CHLORIDE
EINECS 204-517-4
Benzoyl chloride,4-nitro
p-nitrobenzoyl chloride
Benzoyl chloride,p-nitro
4-Nitrobenzoic acid chloride
p-Nitrobenzoic acid chloride
4-(nitro)-benzoyl chloride
4-methyl-quinoline
4-Nitrobenzolcarbonylchlorid
4-NITROBENZOYL CHLORIDE FOR SYNTHESIS
4-Nitrobenzoylchloride
Benzoyl chloride, 4-nitro-
MFCD00007345
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