CSIC E379

Modify Date: 2024-09-14 09:29:28

CSIC E379 Structure
CSIC E379 structure
Common Name CSIC E379
CAS Number 1220476-13-0 Molecular Weight 280.411
Density N/A Boiling Point N/A
Molecular Formula C20H24O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CSIC E379


CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide.

 Names

Name CSIC E379

 CSIC E379 Biological Activity

Description CSIC E379 is a potent, selective uncoupling proteins UCP1/UCP2 inhibitor with EC50 of 20 uM/30 uM, respectively; does not affect OXPHOS system and membrane permeability in liver mitochondria; causes oxidative stress, inhibit the cellular respiration of the cancer cell line HT-29; increases the production of superoxide and decreases the cell viability; potentiates the efficacy of the cytotoxic drug arsenic trioxide.
References References 1. Rial E, et al. Chem Biol. 2011 Feb 25;18(2):264-74. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C20H24O
Molecular Weight 280.411
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