EGFR-IN-9

Modify Date: 2024-01-05 23:12:07

EGFR-IN-9 structure	Common Name	EGFR-IN-9
	CAS Number	1226549-39-8	Molecular Weight	476.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₂₄N₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR-IN-9

EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1].

Name	EGFR-IN-9

Description	EGFR-IN-9 (Compound 8) is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR (WT):7 nM (IC50) EGFRL858R/T790M:28 nM (IC50)
In Vitro	EGFR-IN-9 (Compound 8) shows antiproliferative activity in HCC827 lung cancer cell line with an IC50 of 8 nM.
References	[1]. Coumar MS, et al. Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor leadidentification. J Med Chem. 2010 Jul 8;53(13):4980-8.

Molecular Formula	C₂₉H₂₄N₄O₃
Molecular Weight	476.53

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: EGFR-IN-9
Price: Click To Check
Purity: 99.46%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

EGFR-IN-9 suppliers

EGFR-IN-9 price

EGFR-IN-9

Use of EGFR-IN-9

Names

EGFR-IN-9 Biological Activity

Chemical & Physical Properties