CMB-087229

Modify Date: 2024-04-05 23:03:06

CMB-087229 Structure
CMB-087229 structure
 Common Name CMB-087229
CAS Number 1227692-67-2 Molecular Weight 259.09
Density N/A Boiling Point N/A
Molecular Formula C10H8Cl2N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CMB-087229


CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].

 Names

Name 5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
Synonym More Synonyms

 CMB-087229 Biological Activity

Description CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].
Related Catalog
References

[1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527.

 Chemical & Physical Properties

Molecular Formula C10H8Cl2N2O2
Molecular Weight 259.09

 Synonyms

MFCD31745789
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Chemsrc provides CMB-087229(CAS#:1227692-67-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of CMB-087229 are included as well.>> amp version: CMB-087229

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