Compound 10

Modify Date: 2024-01-05 21:02:23

Compound 10 Structure
Compound 10 structure
Common Name Compound 10
CAS Number 123021-85-2 Molecular Weight 279.26900
Density N/A Boiling Point N/A
Molecular Formula C12H9NO5S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Compound 10


GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].

 Names

Name 2-[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
Synonym More Synonyms

 Compound 10 Biological Activity

Description GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].
Related Catalog
Target

EC50: 1.4 μM (GPR35)[1]. Ki: 0.0508 μM (GPR35)[1]. IC50: 0.349 μM (GPR35)[1].

In Vitro GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1]. GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1].

 Chemical & Physical Properties

Molecular Formula C12H9NO5S
Molecular Weight 279.26900
Exact Mass 279.02000
PSA 121.49000
LogP 1.74980
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
GPR35 Agonist,Compound 10