3'-FLUORO-3'-DEOXYCYTIDINE

Modify Date: 2024-01-11 18:14:17

3'-FLUORO-3'-DEOXYCYTIDINE Structure
3'-FLUORO-3'-DEOXYCYTIDINE structure
Common Name 3'-FLUORO-3'-DEOXYCYTIDINE
CAS Number 123402-20-0 Molecular Weight 245.21
Density 1.82g/cm3 Boiling Point 500.1ºC at 760mmHg
Molecular Formula C9H12FN3O4 Melting Point N/A
MSDS N/A Flash Point 256.2ºC

 Use of 3'-FLUORO-3'-DEOXYCYTIDINE


3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Synonym More Synonyms

 3'-FLUORO-3'-DEOXYCYTIDINE Biological Activity

Description 3′-Deoxy-3′-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.82g/cm3
Boiling Point 500.1ºC at 760mmHg
Molecular Formula C9H12FN3O4
Molecular Weight 245.21
Flash Point 256.2ºC
Exact Mass 245.08100
PSA 111.59000
Vapour Pressure 4.27E-12mmHg at 25°C
Index of Refraction 1.697

 Synonyms

3'-deoxy-3'-fluorocytidine
Cytidine,3'-deoxy-3'-fluoro
3'-fluoro-3'-deoxycytidine
Cytidine,3'-deoxy-3'-fluoro-(9CI)