(8R,9S,10R,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

Modify Date: 2024-04-06 16:34:20

(8R,9S,10R,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one structure	Common Name	(8R,9S,10R,13S,14S,17S)-13,17-diethyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one
	CAS Number	1235-15-0	Molecular Weight	316.47800
	Density	1.09g/cm3	Boiling Point	459.5ºC at 760mmHg
	Molecular Formula	C₂₁H₃₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	195.6ºC

Name	Norbolethone
Synonym	More Synonyms

Density	1.09g/cm3
Boiling Point	459.5ºC at 760mmHg
Molecular Formula	C₂₁H₃₂O₂
Molecular Weight	316.47800
Flash Point	195.6ºC
Exact Mass	316.24000
PSA	37.30000
LogP	4.65940
Vapour Pressure	2.24E-10mmHg at 25°C
Index of Refraction	1.551

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JF7972000

CHEMICAL NAME :: 18,19-Dinor-17-alpha-pregn-4-en-3-one, 13-ethyl-17-hydroxy-, (+-)-

CAS REGISTRY NUMBER :: 1235-15-0

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C21-H32-O2

MOLECULAR WEIGHT :: 316.53

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ E2 FQ F2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5010 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 165 mg/kg

SEX/DURATION :: female 15-25 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 123,867,1966

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 5 mg/kg

SEX/DURATION :: female 15-24 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - parturition

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 123,867,1966

(8R,9S,10R,13S,14S,17S)-13,17-Diethyl-17-hydroxy-1,2,6,7,8,9,10,1 1,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3- one (non-preferred name)