EC-11716 structure
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Common Name | EC-11716 | ||
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CAS Number | 1235486-15-3 | Molecular Weight | 457.959 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H28ClN5O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of EC-11716EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).EC/11716 is active against M. abscessus subspecies and clinical isolates, maintains comparable activity against a panel of clinical isolates covering the M. abscessus complex.EC/11716 is effective against M. abscessus biofilms (MIC 0.78 uM), with better bactericidal activity against biofilms than moxifloxacin.EC/11716 is active against M. abscessus in vivo. |
Name | EC-11716 |
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Description | EC-11716 (EC/11716) is a novel mycobacterium tuberculosis gyrase inhibitor with potent anti-tubercular activity (MIC 0.38 uM, M. tuberculosis H37Rv).EC/11716 is active against M. abscessus subspecies and clinical isolates, maintains comparable activity against a panel of clinical isolates covering the M. abscessus complex.EC/11716 is effective against M. abscessus biofilms (MIC 0.78 uM), with better bactericidal activity against biofilms than moxifloxacin.EC/11716 is active against M. abscessus in vivo. |
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References | 1. Uday S Ganapathy, et al. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0151421. |
Molecular Formula | C23H28ClN5O3 |
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Molecular Weight | 457.959 |