Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU)

Modify Date: 2024-01-05 19:36:27

Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU) Structure
Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU) structure
Common Name Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU)
CAS Number 1240387-33-0 Molecular Weight 426.38
Density 1.47±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C17H22N4O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU)


Description The ureido-4,4´-dibutyric acid bis(hydroxysuccinimide) ester, also known as DSBU or BuUrBU, is the longest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C4-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments.

 Names

Name Urea crosslinker – C₄-arm, NHS ester (DSBU, BuUrBU)
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.47±0.1 g/cm3(Predicted)
Molecular Formula C17H22N4O9
Molecular Weight 426.38
Exact Mass 426.138672
LogP -4.01
Index of Refraction 1.578

 Synonyms

MFCD30738322