Cyclohexanecarboxylicacid

Modify Date: 2024-01-02 16:15:46

Cyclohexanecarboxylicacid structure	Common Name	Cyclohexanecarboxylicacid
	CAS Number	1241-87-8	Molecular Weight	354.309
	Density	1.7±0.1 g/cm3	Boiling Point	636.2±55.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₈O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	234.5±25.0 °C

Use of Cyclohexanecarboxylicacid

1-Caffeoylquinic acid is an effective NF-κB inhibitor, shows significant binding affinity to the RH domain of p105 with Ki of 0.002 μM and binding energy of 1.50 Kcal/mol[1]. 1-Caffeoylquinic acid has anti-oxidative stress ability[2]. 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interact[3].

Name	1-Caffeoylquinic acid
Synonym	More Synonyms

Description	1-Caffeoylquinic acid is an effective NF-κB inhibitor, shows significant binding affinity to the RH domain of p105 with Ki of 0.002 μM and binding energy of 1.50 Kcal/mol[1]. 1-Caffeoylquinic acid has anti-oxidative stress ability[2]. 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interact[3].
Related Catalog	Research Areas >> Cancer
Target	Ki: 0.002 μM (1-Caffeoylquinic acid)[1]
References	[1]. Khan MK, et al. Dietary phytochemicals as potent chemotherapeutic agents against breast cancer: Inhibition of NF-κB pathway via molecular interactions in rel homology domain of its precursor protein p105. Pharmacogn Mag. 2013 Jan;9(33):51-7. [2]. Jiang Y, et al. Caffeoylquinic acid derivatives rich extract from Gnaphalium pensylvanicum willd. Ameliorates hyperuricemia and acute gouty arthritis in animal model. BMC Complement Altern Med. 2017 Jun 17;17(1):320. [3]. Han Y, et al. PD-1/PD-L1 inhibitor screening of caffeoylquinic acid compounds using surface plasmon resonance spectroscopy. Anal Biochem. 2018 Apr 15;547:52-56.

Density	1.7±0.1 g/cm3
Boiling Point	636.2±55.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₈O₉
Molecular Weight	354.309
Flash Point	234.5±25.0 °C
Exact Mass	354.095093
PSA	164.75000
LogP	0.06
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.690