Xanthine-13C,15N2

Modify Date: 2024-01-12 10:45:58

Xanthine-13C,15N2 Structure
Xanthine-13C,15N2 structure
Common Name Xanthine-13C,15N2
CAS Number 1262670-81-4 Molecular Weight 155.09
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C413CH4N215N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Xanthine-13C,15N2


Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

 Names

Name Xanthine-¹³C¹⁵N2
Synonym More Synonyms

 Xanthine-13C,15N2 Biological Activity

Description Xanthine-13C,15N2 is a 15N-labeled and 13C-labled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-244.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-244.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C413CH4N215N2O2
Molecular Weight 155.09
Exact Mass 155.030853
Index of Refraction 1.636

 Synonyms

(2-13C,1,3-15N2)-3,9-Dihydro-1H-purine-2,6-dione
1H-Purine-2,6-dione-2-13C-1,3-15N2, 3,9-dihydro-
Xanthic oxide-13C15N2
1H-Purine-2,6-diol