AM-211 sodium

Modify Date: 2024-03-06 20:25:50

AM-211 sodium Structure
AM-211 sodium structure
Common Name AM-211 sodium
CAS Number 1263077-74-2 Molecular Weight 522.49100
Density N/A Boiling Point N/A
Molecular Formula C27H26F3N2NaO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AM-211 sodium


AM-211 sodium is a novel and potent antagonist of the prostaglandin D2 receptor type 2. AM-211 is active in animal models of allergic inflammation. AM211 has high affinity for human, mouse, rat, and guinea pig DP2 and it shows selectivity over other prostanoid receptors and enzymes. AM211 exhibits good oral bioavailability in rats and dogs and dose-dependently inhibits 13,14-dihydro-15-keto-PGD(2)-induced leukocytosis in a guinea pig pharmacodynamic assay.

 Names

Name sodium,2-[3-[2-[[benzylcarbamoyl(ethyl)amino]methyl]-4-(trifluoromethyl)phenyl]-4-methoxyphenyl]acetate
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C27H26F3N2NaO4
Molecular Weight 522.49100
Exact Mass 522.17400
PSA 85.19000
LogP 4.60950

 Synonyms

AM-211 sodium
UNII-8SV621U288
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