Melarsomine

Modify Date: 2024-01-05 07:28:25

Melarsomine Structure
Melarsomine structure
Common Name Melarsomine
CAS Number 128470-15-5 Molecular Weight 428.41100
Density N/A Boiling Point 678.1ºC at 760mmHg
Molecular Formula C13H21AsN8S2 Melting Point N/A
MSDS N/A Flash Point 363.9ºC

 Use of Melarsomine


Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].

 Names

Name 2-N-[4-[bis(2-aminoethylsulfanyl)arsanyl]phenyl]-1,3,5-triazine-2,4,6-triamine
Synonym More Synonyms

 Melarsomine Biological Activity

Description Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections[1][2].
Related Catalog
In Vivo Melarsomine (2.5 mg/kg; deep i.m. injection) combined with Doramectin managed to clear the D. repens infection in dogs[1]. Melarsomine (0.25 mg/kg; deep i.m. injection) can cure T. evansi infection in camels[2]. Melarsomine (0.5 mg/kg; deep i.m. injection) can cure T. evansi infection in dairy cattle in Thailand[2].
References

[1]. Baneth G, et, al. Dirofilaria repens infection in a dog: diagnosis and treatment with melarsomine and doramectin. Vet Parasitol. 2002 Apr 30;105(2):173-8.

[2]. Desquesnes M, et, al. An evaluation of melarsomine hydrochloride efficacy for parasitological cure in experimental infection of dairy cattle with Trypanosoma evansi in Thailand. Parasitology. 2011 Aug;138(9):1134-42.

 Chemical & Physical Properties

Boiling Point 678.1ºC at 760mmHg
Molecular Formula C13H21AsN8S2
Molecular Weight 428.41100
Flash Point 363.9ºC
Exact Mass 428.05500
PSA 205.38000
LogP 2.49460
Vapour Pressure 3.03E-18mmHg at 25°C

 Synonyms

Melarsomine
Melarsominum [INN-Latin]
Melarsomina
Melarsomina [INN-Spanish]
Bis(2-aminoethyl) p-((4,6-diamino-s-triazin-2-yl)amino)dithiobenzenearsonite
Melarsomine (INN)
Melarsominum
UNII-374GJ0S41A