(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

Modify Date: 2024-01-09 20:30:54

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt structure	Common Name	(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt
	CAS Number	129622-68-0	Molecular Weight	3478.06
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₆₂H₂₅₄N₅₀O₃₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist[1][2].

Name	(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt
Synonym	More Synonyms

Description	(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist[1][2].
Related Catalog	Research Areas >> Metabolic Disease
Target	PTH1R
References	[1]. Nutt RF, et al. Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. Endocrinology. 1990 Jul;127(1):491-3. [2]. Portal-Núñez S, et al. Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains. Bone Joint Res. 2018 Jan;7(1):58-68.

Density	1.4±0.1 g/cm3
Molecular Formula	C₁₆₂H₂₅₄N₅₀O₃₆
Molecular Weight	3478.06
Exact Mass	3475.958252
LogP	0.51
Index of Refraction	1.664

L-Leucyl-L-leucyl-L-histidyl-L-asparaginyl-L-leucyl-D-tryptophyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-L-leucyl -L-histidyl-L-histidyl-L-leucyl-L-isoleucyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-histidyl-L-threonyl-L-alaninamide

MFCD00214657

L-Alaninamide, L-leucyl-L-leucyl-L-histidyl-L-asparaginyl-L-leucyl-D-tryptophyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-α-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-phenylalanyl-L-phenyl alanyl-L-leucyl-L-histidyl-L-histidyl-L-leucyl-L-isoleucyl-L-alanyl-L-α-glutamyl-L-isoleucyl-L-histidyl-L-threonyl-

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

Use of (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) trifluoroacetate salt

Names

Biological Activity

Chemical & Physical Properties

Synonyms