N-Acetylneuraminic acid

Modify Date: 2024-01-01 21:11:40

N-Acetylneuraminic acid Structure
N-Acetylneuraminic acid structure
 Common Name N-Acetylneuraminic acid
CAS Number 131-48-6 Molecular Weight 309.270
Density 1.6±0.1 g/cm3 Boiling Point 762.3±60.0 °C at 760 mmHg
Molecular Formula C11H19NO9 Melting Point 184-186 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 414.8±32.9 °C

 Use of N-Acetylneuraminic acid


N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.

 Names

Name N-acetylneuraminic acid
Synonym More Synonyms

 N-Acetylneuraminic acid Biological Activity

Description N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.

[2]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 762.3±60.0 °C at 760 mmHg
Melting Point 184-186 °C (dec.)(lit.)
Molecular Formula C11H19NO9
Molecular Weight 309.270
Flash Point 414.8±32.9 °C
Exact Mass 309.105988
PSA 176.78000
LogP -3.98
Vapour Pressure 0.0±5.8 mmHg at 25°C
Index of Refraction 1.581
Water Solubility 50 g/L (20 ºC)

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2932999099

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles104

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Glycobiology 25 , 784-91, (2015)

Human sialidases (NEUs) catalyze the removal of N-acetyl neuraminic acids from the glycome of the cell and regulate a diverse repertoire of nominal cellular functions, such as cell signaling and adhes...

 Synonyms

5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid
NANA
5-(acetylamino)-3,5-dideoxy-δ-glycero-δ-galacto-2-Nonulosonic acid
NANA H2O
Sialomucin
sialic acid powder
Lactaminic acid
5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid
N-acetyl-D-neuraminic acid
5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid
5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosonic acid,Lactaminic acid,NAN
O-SIALIC ACID
NANA TYPE IV-S
NEU5AC
D-glycero-D-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy-
sialic acid
NANA TYPE VI
EINECS 205-023-1
5-(Acetylamino)-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic Acid
NAN
(4S,5R,6R,7S,8R)-5-Acetamido-4,6,7,8,9-pentahydroxy-2-oxononanoic acid
Aceneuramic acid
N-Acetylneuraminic acid
MFCD00006620
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