CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XG5970000
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CHEMICAL NAME :
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Thallium oxide
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CAS REGISTRY NUMBER :
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1314-12-1
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LAST UPDATED :
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199701
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DATA ITEMS CITED :
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8
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MOLECULAR FORMULA :
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O-Tl2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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40600 ug/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage
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REFERENCE :
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85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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75 mg/kg
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TOXIC EFFECTS :
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Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair
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REFERENCE :
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85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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31200 ug/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage
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REFERENCE :
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85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Mammal - dog
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DOSE/DURATION :
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31200 ug/kg
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TOXIC EFFECTS :
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Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair
-
REFERENCE :
-
85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
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TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
-
31200 ug/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage
-
REFERENCE :
-
85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
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SPECIES OBSERVED :
-
Rodent - rabbit
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DOSE/DURATION :
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62400 ug/kg
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TOXIC EFFECTS :
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Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair
-
REFERENCE :
-
85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
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TYPE OF TEST :
-
LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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40600 ug/kg
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TOXIC EFFECTS :
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Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair
-
REFERENCE :
-
85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978
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