4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione

Modify Date: 2024-01-06 11:09:46

4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione Structure
4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione structure
Common Name 4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione
CAS Number 13239-97-9 Molecular Weight 259.28
Density 1.9±0.1 g/cm3 Boiling Point 540.5±60.0 °C at 760 mmHg
Molecular Formula C9H13N3O4S Melting Point 208-209 °C (lit.)
MSDS N/A Flash Point 280.7±32.9 °C

 Use of 4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione


2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-thiocytidine
Synonym More Synonyms

  Biological Activity

Description 2-Thiocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 540.5±60.0 °C at 760 mmHg
Melting Point 208-209 °C (lit.)
Molecular Formula C9H13N3O4S
Molecular Weight 259.28
Flash Point 280.7±32.9 °C
Exact Mass 259.062683
PSA 145.85000
LogP -1.33
Vapour Pressure 0.0±3.3 mmHg at 25°C
Index of Refraction 1.788

 Synonyms

4-Amino-1-pentofuranosyl-2(1H)-pyrimidinethione
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2-thione
2-Thiocytidin
EINECS 236-214-8
2-Thiocytidine
2(1H)-Pyrimidinethione, 4-amino-1-pentofuranosyl-
MFCD00167106
Cytidine,2-thio
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