Xipamide-d6

Modify Date: 2024-01-18 12:00:43

Xipamide-d6 structure	Common Name	Xipamide-d6
	CAS Number	1330262-09-3	Molecular Weight	360.84600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₉ClD₆N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Xipamide-d6

Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1][2].

Name	N-[2,6-bis(trideuteriomethyl)phenyl]-4-chloro-2-hydroxy-5-sulfamoylbenzamide
Synonym	More Synonyms

Description	Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE)[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Prichard BN, et al. Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1985 Oct;30(4):313-32. [3]. Hannaert P, et al. Beneficial effects of xipamide on pH and Ca2+ ions of cardiac cells. Arch Mal Coeur Vaiss. 1990 Jul;83(8):1271-4.

Molecular Formula	C₁₅H₉ClD₆N₂O₄S
Molecular Weight	360.84600
Exact Mass	360.08200
PSA	121.36000
LogP	4.72720

Diurex-d6

Lumitens-d6

Xipamide-d6

Aquaphor-d6

4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide-d6

Chronexan-d6

Xipamide-d6

Use of Xipamide-d6

Names

Xipamide-d6 Biological Activity

Chemical & Physical Properties

Synonyms