L-5,6,7,8-Tetrahydrofolic acid structure
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Common Name | L-5,6,7,8-Tetrahydrofolic acid | ||
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CAS Number | 135-16-0 | Molecular Weight | 445.42900 | |
Density | 1.7g/cm3 | Boiling Point | 555.12°C (rough estimate) | |
Molecular Formula | C19H23N7O6 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Use of L-5,6,7,8-Tetrahydrofolic acidL-5,6,7,8-Tetrahydrofolic acid, a folic acid derivative, which is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. |
Name | 5,6,7,8-tetrahydrofolic acid |
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Synonym | More Synonyms |
Description | L-5,6,7,8-Tetrahydrofolic acid, a folic acid derivative, which is a coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
Density | 1.7g/cm3 |
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Boiling Point | 555.12°C (rough estimate) |
Molecular Formula | C19H23N7O6 |
Molecular Weight | 445.42900 |
Exact Mass | 445.17100 |
PSA | 211.56000 |
LogP | 1.03910 |
Appearance of Characters | powder | off-white to tan |
Index of Refraction | 1.762 |
Storage condition | −20°C |
Stability | We have observed that this material decomposes steadily over time. Use immediately upon receipt. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | MA0600800 |
HS Code | 2933990090 |
~57% L-5,6,7,8-Tetra... CAS#:135-16-0 |
Literature: Zhou, Minghao; Hong, Mei; Xiao, Guomin Research on Chemical Intermediates, 2013 , vol. 39, # 5 p. 2211 - 2218 |
~% L-5,6,7,8-Tetra... CAS#:135-16-0 |
Literature: Antimicrobial Agents and Chemotherapy, , vol. 57, # 10 p. 4990 - 4998 |
~69% L-5,6,7,8-Tetra... CAS#:135-16-0 |
Literature: Charlton, Peter A.; Young, Douglas W.; Birdsall, Berry; Feeney, James; Roberts, Gordon C. K. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1349 - 1354 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Quantitation of 5-Methyltetrahydrofolic Acid in Dried Blood Spots and Dried Plasma Spots by Stable Isotope Dilution Assays.
PLoS ONE 10 , e0143639, (2015) Because of minimal data available on folate analysis in dried matrix spots (DMSs), we combined the advantages of stable isotope dilution assays followed by LC-MS/MS analysis with DMS sampling to devel... |
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Arg-265: a critical residue of L.donovani cytosolic SHMT in maintaining the binding of THF and catalysis.
Exp. Parasitol. 149 , 16-23, (2015) Serine hydroxymethyltransferase belongs to the class of pyridoxal-5-phosphate enzymes along with aspartate aminotransferase. To explore the function of residue(s) involved in binding of the carboxylat... |
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Folate levels measured by LC-MS/MS in patients with colorectal cancer treated with different leucovorin dosages.
Cancer Chemother. Pharmacol. 74(6) , 1167-74, (2014) Calcium folinate (leucovorin), which is converted in vivo into biologically active folate, enhances the potency of 5-fluorouracil (5-FU)-based chemotherapy in colorectal cancer. A common dosage of leu... |
Tetrahydrofolic acide |
Tetrahydropteroylglutaamic acid |
(6S)-Tetrahydrofolic acid |
l-amino)benzoyl) |
TETRAHYDROFOLIC ACID |
EINECS 205-181-1 |
5,6,7,8-tetrahydrofolicacid |
L-5,6,7,8-Tetrahydrofolic acid |
MFCD00135583 |
(6S)-Thfa |
tetrahydropteroylglutamicacid |
(6R,6S)-tetrahydrofolic acid |
(6RS)-5,6,7,8-Tetrahydro-L-folsaeure |