SAR127303

Modify Date: 2024-04-06 16:45:21

SAR127303 structure	Common Name	SAR127303
	CAS Number	1352011-38-1	Molecular Weight	482.83
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₇ClF₆N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SAR127303

SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.

Name	SAR127303

Description	SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.
References	1. Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH. Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics. 2016 May 21;6(8):1145-59. doi: 10.7150/thno.15257. eCollection 2016. PubMed PMID: 27279908; PubMed Central PMCID: PMC4893642.

Description

SAR127303 is an effective covalent inhibitor of MAGL. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL.

References

1. Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH. Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics. 2016 May 21;6(8):1145-59. doi: 10.7150/thno.15257. eCollection 2016. PubMed PMID: 27279908; PubMed Central PMCID: PMC4893642.

Molecular Formula	C₁₆H₁₇ClF₆N₂O₄S
Molecular Weight	482.83

SAR127303

Use of SAR127303

Names

SAR127303 Biological Activity

Chemical & Physical Properties