URB 937

Modify Date: 2024-01-07 19:29:25

URB 937 Structure
URB 937 structure
Common Name URB 937
CAS Number 1357160-72-5 Molecular Weight 354.400
Density 1.3±0.1 g/cm3 Boiling Point 562.8±50.0 °C at 760 mmHg
Molecular Formula C20H22N2O4 Melting Point N/A
MSDS USA Flash Point 294.2±30.1 °C

 Use of URB 937


URB937 is a potent fatty acid amide hydrolase (FAAH) inhibitor (IC50 = 26.8 nM, in vitro) that does not penetrate the blood-brain barrier, thus preventing arachidonoyl ethanolamidedeactivation only in peripheral tissues.

 Names

Name urb937
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 562.8±50.0 °C at 760 mmHg
Molecular Formula C20H22N2O4
Molecular Weight 354.400
Flash Point 294.2±30.1 °C
Exact Mass 354.157959
PSA 101.65000
LogP 2.38
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.639

 Safety Information

RIDADR NONH for all modes of transport

 Synthetic Route

~93%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; Location in patent: Page/Page column 27 ; WO 2012/015704 A2

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URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

~%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

~%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; UNIVERSITA DEGLI STUDI DI URBINO "CARLO BO"; UNIVERSITA DEGLI STUDI DI PARMA; PIOMELLI, Daniele; CLAPPER, Jason, R.; MORENO-SANZ, Guillermo; DURANTI, Andrea; TONTINI, Andrea; MOR, Marco; TARZIA, Giorgio Patent: WO2012/15704 A2, 2012 ; WO 2012/015704 A2

~%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367

~%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367

~%

URB 937 Structure

URB 937

CAS#:1357160-72-5

Literature: Fiorelli, Claudio; Scarpelli, Rita; Piomelli, Daniele; Bandiera, Tiziano Organic Process Research and Development, 2013 , vol. 17, # 3 p. 359 - 367

 Synonyms

cyclohexylcarbamic acid 3'-carbamoyl-6-hydroxybiphenyl-3-yl ester
3'-Carbamoyl-6-hydroxy-3-biphenylyl cyclohexylcarbamate
Cyclohexylcarbaldehyddiallylacetal
Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)-6-hydroxy[1,1'-biphenyl]-3-yl ester
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