P32/98
Modify Date: 2024-01-05 19:08:33
P32/98 structure
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Common Name | P32/98 | ||
|---|---|---|---|---|
| CAS Number | 136259-20-6 | Molecular Weight | 520.70600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H40N4O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of P32/98P32/98 is a potent inhibitor of dipeptidyl peptidase IV. P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in preclinical studies using the fatty Zucker rat, an animal model for IGT (impaired glucose tolerance)[1]. |
| Name | 2-amino-3-methyl-1-(1,3-thiazolidin-3-yl)pentan-1-one,but-2-enedioic acid |
|---|---|
| Synonym | More Synonyms |
| Description | P32/98 is a potent inhibitor of dipeptidyl peptidase IV. P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in preclinical studies using the fatty Zucker rat, an animal model for IGT (impaired glucose tolerance)[1]. |
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| Related Catalog | |
| Target |
DPP4[1] |
| In Vivo | P32/98 (25 mg/kg; i.g.; once daily) long-time treatment significantly improves the glucose tolerance in Zucker diabetic fatty rats[2]. Animal Model: Zucker diabetic fatty rat[2] Dosage: 25 mg/kg Administration: i.g., once daily Result: Significantly improved the glucose tolerance in Zucker diabetic fatty rats. |
| References |
| Molecular Formula | C22H40N4O6S2 |
|---|---|
| Molecular Weight | 520.70600 |
| Exact Mass | 520.23900 |
| PSA | 217.86000 |
| LogP | 2.77360 |
| P32/98 |
| L-threo-isoleucyl thiazolidine |
| isoleucine thiazolide |
| L-threo-isoleucyl rhiazolidine |